Do the balloon tips keep annoying you? Then don’t worry, here’s how you can disable notification area balloon tips in Windows Vista:

1. First Go to Start > Run and type Regedit.exe

2. Navigate to the following subkey:

HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced

3. Create a new REG_DWORD (32 bit) value, and then name it EnableBalloonTips

4. Double-click EnableBalloonTips, and then give it a value of 0

5. Close Regedit.exe

6. Log off Windows, and then log back on.

If you dont want to do the above method you can download the below file and just run it.
Download From Here - Disableballoontips.reg

Source - BizznTech